Article
Genome-Wide Methylation of Mild Cognitive Impairment in Mexican Americans Highlights Genes Involved in Synaptic Transport, Alzheimer's Disease-Precursor Phenotypes, and Metabolic Morbidities.
Journal of Alzheimer's disease : JAD - 1 Jan 2019
Pathak Gita A, Silzer Talisa K, Sun Jie, Zhou Zhengyang, Daniel Ann A, Johnson Leigh, O'Bryant Sid, Phillips Nicole R, Barber Robert C
Abstract excerpt
The Mexican American population is among the fastest growing aging population and has a younger onset of cognitive decline. This group is also heavily burdened with metabolic conditions such as hypertension, diabetes, and obesity. Unfortunately, limited research has been conducted in this group. Understanding methylation alterations, which are influenced by both genetic and lifestyle factors, is key to...
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