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Differential DNA methylation in blood in nuclear genes that encode mitochondrial proteins in mild cognitive impairment and Alzheimer’s disease

2025-06-20

Abstract excerpt

<h4>Background</h4> Altered mitochondrial function contributes to the pathogenesis of mild cognitive impairment (MCI) and late-onset dementia due to Alzheimer’s disease (AD). <h4>Objective</h4> To test for differential methylation in nuclear genes that encode proteins that participate in mitochondrial function between cognitively unimpaired participants (CU) and those with MCI and AD. <h4>Methods</h4> Recently...

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Identifiers and source

Literature Corpus work
24ac52d2-f12c-54ca-be84-d3a8dbc59137
DOI
10.1101/2025.06.16.659556
Open publication

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Differential DNA methylation in blood in nuclear genes that encode mitochondrial proteins in mild cognitive impairment and Alzheimer’s diseaseDOI 10.1101/2025.06.16.659556
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