An engineered ultra‐high affinity Fab‐Protein G pair enables a modular antibody platform with multifunctional capability

Abstract excerpt

Abstract Engineered recombinant antibody‐based reagents are rapidly supplanting traditionally derived antibodies in many cell biological applications. A particularly powerful aspect of these engineered reagents is that other modules having myriad functions can be attached to them either chemically or through molecular fusions. However, these processes can be cumbersome and do not lend themselves to high...

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