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Vimentin filaments interact with the actin cortex in mitosis allowing normal cell division

13 Sept 2019

Abstract excerpt

The vimentin network displays remarkable plasticity to support basic cellular functions and reorganizes during cell division. Here, we show that in several cell types vimentin filaments redistribute to the cell cortex during mitosis, forming a robust framework interwoven with cortical actin and affecting its organization. Importantly, the intrinsically disordered tail domain of vimentin is essential for this...

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PMID: 31519880
DOI: 10.1038/s41467-019-12029-4

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