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Article

Intermediate Filaments Play a Pivotal Role in Regulating Cell Architecture and Function.

The Journal of biological chemistry - 10 Jul 2015

Lowery Jason, Kuczmarski Edward R, Herrmann Harald, Goldman Robert D

Abstract excerpt

Intermediate filaments (IFs) are composed of one or more members of a large family of cytoskeletal proteins, whose expression is cell- and tissue type-specific. Their importance in regulating the physiological properties of cells is becoming widely recognized in functions ranging from cell motility to signal transduction. IF proteins assemble into nanoscale biopolymers with unique strain-hardening properties that...

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Identifiers

PMID: 25957409
DOI: 10.1074/jbc.R115.640359
PMCID: PMC4498054

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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