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Cell cycle regulators control mesoderm specification in human pluripotent stem cells

12 Sept 2019

Abstract excerpt

The mesoderm is one of the three germ layers produced during gastrulation from which muscle, bones, kidneys, and the cardiovascular system originate. Understanding the mechanisms that control mesoderm specification could inform many applications, including the development of regenerative medicine therapies to manage diseases affecting these tissues. Here, we used human pluripotent stem cells to investigate the...

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PMID: 31515269
DOI: 10.1074/jbc.ra119.008251

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