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Article

Genome-wide functional analysis of human cell-cycle regulators.

Proceedings of the National Academy of Sciences of the United States of America - 3 Oct 2006

Mukherji Mridul, Bell Russell, Supekova Lubica, Wang Yan, Orth Anthony P, Batalov Serge, Miraglia Loren, Huesken Dieter, Lange Joerg, Martin Christopher, Sahasrabudhe Sudhir, Reinhardt Mischa, Natt Francois, Hall Jonathan, Mickanin Craig, Labow Mark, Chanda Sumit K, Cho Charles Y, Schultz Peter G

Abstract excerpt

Human cells have evolved complex signaling networks to coordinate the cell cycle. A detailed understanding of the global regulation of this fundamental process requires comprehensive identification of the genes and pathways involved in the various stages of cell-cycle progression. To this end, we report a genome-wide analysis of the human cell cycle, cell size, and proliferation by targeting >95% of the...

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Identifiers

PMID: 17001007
DOI: 10.1073/pnas.0604320103
PMCID: PMC1595435

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TNF

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