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AMPK Subunits Harbor Largely Nonoverlapping Genetic Determinants for Body Fat Mass, Glucose Metabolism, and Cholesterol Metabolism

12 Sept 2019

Abstract excerpt

CONTEXT: Adenosine monophosphate (AMP)-activated protein kinase (AMPK) is a heterotrimeric enzyme and central regulator of cellular energy metabolism. The impact of single nucleotide polymorphisms (SNPs) in all 7 AMPK subunit genes on adiposity, glucose metabolism, and lipid metabolism has not yet been systematically studied. OBJECTIVE: To analyze the associations of common SNPs in all AMPK genes, and of...

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Share to Adipokines, Inflammation, and Metabolic Diseases
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PMID: 31512724
DOI: 10.1210/clinem/dgz020

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