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Article

Ataxia-telangiectasia mutated is required for the development of protective immune memory after influenza A virus infection.

American journal of physiology. Lung cellular and molecular physiology - 1 Nov 2019

Warren Rachel, Domm William, Yee Min, Campbell Andrew, Malone Jane, Wright Terry, Mayer-Pröschel Margot, O'Reilly Michael A

Abstract excerpt

Ataxia-telangiectasia (A-T), caused by mutations in the A-T mutated (ATM) gene, is a neurodegenerative disorder affecting ∼1 in 40,000-100,000 children. Recurrent respiratory infections are a common and challenging comorbidity, often leading to the development of bronchiectasis in individuals with A-T. The role of ATM in development of immune memory in response to recurrent respiratory viral infections is not...

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Identifiers

PMID: 31509427
DOI: 10.1152/ajplung.00031.2019
PMCID: PMC6879906

Genes

ATM

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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