Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Ataxia Telangiectasia Mutated Kinase Controls Chronic Gammaherpesvirus Infection

20 Sept 2012

Abstract excerpt

Gammaherpesviruses, such as Epstein-Barr virus (EBV), are ubiquitous cancer-associated pathogens that interact with DNA damage response, a tumor suppressor network. Chronic gammaherpesvirus infection and pathogenesis in a DNA damage response-insufficient host are poorly understood. Ataxia-telangiectasia (A-T) is associated with insufficiency of ataxia-telangiectasia mutated (ATM), a critical DNA damage response...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cytomegalovirus and herpesvirus research
Share to Herpesvirus Infections and Treatments
Share to Viral-associated cancers and disorders

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 22993144
DOI: 10.1128/jvi.00917-12

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Ataxia Telangiectasia Mutated Kinase Controls Chronic Gammaherpesvirus InfectionPMID 22993144Read ↗

Epstein-Barr Virus (EBV)-Related Lymphoproliferative Disorders in Ataxia Telangiectasia: Does ATM Regulate EBV Life Cycle?Semantic proximity Read ↗

ATM activity in T cells is critical for immune surveillance of lymphoma in vivo.Semantic proximity Read ↗

The amplitude of gammaherpesvirus lytic replication dictates adaptive immune activation: Potential implications for KSHV LANA in immune evasionSemantic proximity Read ↗

Immunodeficiencies that predispose to pathologies by human oncogenic γ-herpesviruses.Semantic proximity Read ↗

Ataxia-telangiectasia mutated is required for the development of protective immune memory after influenza A virus infection.Semantic proximity Read ↗

Conserved gammaherpesvirus kinase and histone variant H2AX facilitate gammaherpesvirus latency in vivo.Semantic proximity Read ↗

Gammaherpesviruses and B Cells: A Relationship That Lasts a LifetimeSemantic proximity Read ↗

Atm-deficient mice: a paradigm of ataxia telangiectasia.Semantic proximity Read ↗

p53 Controls Murine Gammaherpesvirus Latency and Prevents Infection-Associated <i>IgH/c-Myc</i> TranslocationsSemantic proximity Read ↗

Host Genetic Variation Has a Profound Impact on Immune Responses Mediating Control of Viral Load in Chronic Gammaherpesvirus Infection.Semantic proximity Read ↗

Kinase-dead ATM protein causes genomic instability and early embryonic lethality in mice.Semantic proximity Read ↗

Insufficiency of DNA repair enzyme ATM promotes naive CD4 T-cell loss in chronic hepatitis C virus infectionSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.