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Atomoxetine produces oxidative stress and alters mitochondrial function in human neuron-like cells

10 Sept 2019

Abstract excerpt

Atomoxetine (ATX) is a non-stimulant drug used in the treatment of attention-deficit/hyperactivity disorder (ADHD) and is a selective norepinephrine reuptake inhibitor. It has been shown that ATX has additional effects beyond the inhibition of norepinephrine reuptake, affecting several signal transduction pathways and alters gene expression. Here, we study alterations in oxidative stress and mitochondrial...

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PMID: 31506604
DOI: 10.1038/s41598-019-49609-9

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