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Antidepressant Action on Mitochondrial Dysfunction in Psychiatric Disorders

19 Aug 2016

Abstract excerpt

Preclinical Research Mitochondria are cell organelles crucial to the production of cellular energy. Several lines of evidence have indicated that mitochondrial dysfunction could be related to the pathophysiology of CNS diseases including bipolar disorder, major depressive disorder, and schizophrenia. These changes include impaired energy metabolism in the brain, co-morbidity with mitochondrial diseases, the...

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PMID: 27539538
DOI: 10.1002/ddr.21332

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