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Article

Atomoxetine affects transcription/translation of the NMDA receptor and the norepinephrine transporter in the rat brain &ndash; an in vivo study

1 Dec 2013

Abstract excerpt

Attention-deficit/hyperactivity disorder (ADHD) is the most frequently diagnosed neurodevelopmental disorder. The norepinephrine transporter (NET) inhibitor atomoxetine, the first nonstimulant drug licensed for ADHD treatment, also acts as an N-methyl-D-aspartate receptor (NMDAR) antagonist. The compound's effects on gene expression and protein levels of NET and NMDAR subunits (1, 2A, and 2B) are unknown....

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PMID: 24348020
DOI: 10.2147/dddt.s50448

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