Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Mitochondrial DNA variation modulates alveolar development in newborn mice exposed to hyperoxia.

American journal of physiology. Lung cellular and molecular physiology - 1 Dec 2019

Kandasamy Jegen, Rezonzew Gabriel, Jilling Tamas, Ballinger Scott, Ambalavanan Namasivayam

Abstract excerpt

Hyperoxia-induced oxidant stress contributes to the pathogenesis of bronchopulmonary dysplasia (BPD) in preterm infants. Mitochondrial functional differences due to mitochondrial DNA (mtDNA) variations are important modifiers of oxidant stress responses. The objective of this study was to determine whether mtDNA variation independently modifies lung development and mechanical dysfunction in newborn mice exposed...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Animals, Newborn
Share to Energy Metabolism

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Hyperoxia

Share to Mice, Inbred C3H

Share to Mitochondria

Share to Pulmonary Alveoli

Share to Superoxides

Source

Open in PubMed Open full text

Identifiers

PMID: 31432715
DOI: 10.1152/ajplung.00220.2019
PMCID: PMC6962596

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Mitochondrial DNA variation modulates alveolar development in newborn mice exposed to hyperoxia.PMID 31432715Read ↗

Mitochondrial DNA Variations Modulate Alveolar Epithelial Mitochondrial Function and Oxidative Stress in Newborn Mice Exposed to HyperoxiaSemantic proximity Read ↗

Effects of Hyperoxia on Mitochondrial Homeostasis: Are Mitochondria the Hub for Bronchopulmonary Dysplasia?Semantic proximity Read ↗

Mouse lung development and NOX1 induction during hyperoxia are developmentally regulated and mitochondrial ROS dependentSemantic proximity Read ↗

Sex-specific differences in primary neonatal murine lung fibroblasts exposed to hyperoxia in vitro: implications for bronchopulmonary dysplasiaSemantic proximity Read ↗

Genome-wide association mapping of acute lung injury in neonatal inbred mice.Semantic proximity Read ↗

Single-cell transcriptomics reveals lasting changes in the lung cellular landscape into adulthood after neonatal hyperoxic exposureSemantic proximity Read ↗

Animal models of bronchopulmonary dysplasia. The term mouse modelsSemantic proximity Read ↗

Differences in reactive oxygen species production explain the phenotypes associated with common mouse mitochondrial DNA variants.Semantic proximity Read ↗

Role of sex as a biological variable in neonatal alveolar macrophagesSemantic proximity Read ↗

Superoxide dismutase 3, extracellular (SOD3) variants and lung function.Semantic proximity Read ↗

Genetic variation in the activity of a TREM2-p53 signaling axis determines oxygen-induced lung injury.Semantic proximity Read ↗

Long-term effects of recurrent intermittent hypoxia and hyperoxia on respiratory system mechanics in neonatal mice.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.