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Finding of Agr Phase Variants in Staphylococcus aureus

5 Aug 2019

Abstract excerpt

Staphylococcus aureus is responsible for a broad range of infections. This pathogen has a vast arsenal of virulence factors at its disposal, but avirulent strains are frequently isolated as the cause of clinical infections. These isolates have a mutated agr locus and have been believed to have no evolutionary future. Here we show that a fraction of Agr-negative strains can repair their mutated agr locus with...

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PMID: 31387900
DOI: 10.1128/mbio.00796-19

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