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Article

Mutations in agr do not persist in natural populations of methicillin-resistant Staphylococcus aureus.

The Journal of infectious diseases - 15 Nov 2010

Shopsin Bo, Eaton Christian, Wasserman Gregory A, Mathema Barun, Adhikari Rajan P, Agolory Simon, Altman Deena R, Holzman Robert S, Kreiswirth Barry N, Novick Richard P

Abstract excerpt

Staphylococcus aureus organisms vary in the function of the staphylococcal virulence regulator gene agr. To test for a relationship between agr and transmission in S. aureus, we determined the prevalence and genetic basis of agr dysfunction among nosocomial methicillin-resistant S. aureus (MRSA) in an area of MRSA endemicity. Identical inactivating agr mutations were not detected in epidemiologically unlinked...

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PMID: 20942648
DOI: 10.1086/656915

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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