Article
Mutation of Agr Is Associated with the Adaptation of Staphylococcus aureus to the Host during Chronic Osteomyelitis.
Frontiers in cellular and infection microbiology - 1 Jan 2018
Suligoy Carlos M, Lattar Santiago M, Noto Llana Mariángeles, González Cintia D, Alvarez Lucía P, Robinson D Ashley, Gómez Marisa I, Buzzola Fernanda R, Sordelli Daniel O
Abstract excerpt
Selection pressures exerted on Staphylococcus aureus by host factors may lead to the emergence of mutants better adapted to the evolving conditions at the infection site. This study was aimed at identifying the changes that occur in S. aureus exposed to the host defense mechanisms during chronic osteomyelitis and evaluating whether these changes affect the virulence of the organism. Genome assessment of two S....
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