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Article

Functionalization of CD36 cardiovascular disease and expression associated variants by interdisciplinary high throughput analysis

25 Jul 2019

Abstract excerpt

CD36 is a platelet membrane glycoprotein whose engagement with oxidized low-density lipoprotein (oxLDL) results in platelet activation. The CD36 gene has been associated with platelet count, platelet volume, as well as lipid levels and CVD risk by genome-wide association studies. Platelet CD36 expression levels have been shown to be associated with both the platelet oxLDL response and an elevated risk of...

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PMID: 31344026
DOI: 10.1371/journal.pgen.1008287

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