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Haplotypes analysis reveals the genetic basis of type I CD36 deficiency.

Scientific reports - 14 Oct 2024

Xia Wenjie, Chen Dawei, Li Xinnian, Liu Jing, Xu Xiuzhang, Ye Xin, Deng Jing, Ding Haoqiang, Ren Hui, Chen Yangkai, Liang Huaqin, Lai Xingqiang, Fu Yongshui

Abstract excerpt

CD36, also known as glycoprotein IV, is classified into two distinct subgroups based on the presence or absence of its expression on monocytes. The CD36 gene spans approximately 50,000 base pairs. Historically, research has focused on identifying CD36 mutations through Sanger sequencing and next-generation sequencing (NGS), with limited exploration of haplotypes. In this study, we collected blood samples from...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 39402159
DOI: 10.1038/s41598-024-74917-0
PMCID: PMC11473821

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