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Article

Transcriptomic Profiling of the Developing Cardiac Conduction System at Single-Cell Resolution

9 Jul 2019

Abstract excerpt

RATIONALE: The cardiac conduction system (CCS) consists of distinct components including the sinoatrial node, atrioventricular node, His bundle, bundle branches, and Purkinje fibers. Despite an essential role for the CCS in heart development and function, the CCS has remained challenging to interrogate because of inherent obstacles including small cell numbers, large cell-type heterogeneity, complex anatomy, and...

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PMID: 31284824
DOI: 10.1161/circresaha.118.314578

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