Article

A CTC Model Uncovers Metastatic Drivers and Prognostic Markers in Breast Cancer

2025-01-17

Abstract excerpt

<h4>Background: </h4> Circulating tumor cells (CTCs) and CTC-clusters are pivotal in the metastatic process of breast cancer (BC). Owing to their low frequency, models replicating their biology should provide a robust platform for investigating the molecular mechanisms driving metastasis and identifying new biomarkers. We established and characterized a CTC-derived cell model from a mouse xenograft to explore its...

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Literature Corpus work: 1ed68a3a-149d-590b-b222-189429fd6633
DOI: 10.1101/2025.01.16.25320597

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