Article
Polymorphisms in MMP-14 and MMP-2 genes and ovarian cancer survival.
Cancer biomarkers : section A of Disease markers - 1 Jan 2019
Vos M Caroline, van Tilborg Angela, Brands William J, Boll Dorry, van Hamont Dennis, van der Putten Hans, Pijlman Brenda, van der Wurff Anneke A M, van Kuppevelt Toin H, Massuger Leon F A G
Abstract excerpt
BACKGROUND: Functional polymorphisms in matrix metalloproteinases can increase or decrease the risk of cancer. This study focused on ovarian cancer and investigated how polymorphisms in the coding region of MMP-14 and the promoter region of MMP-2 are related to clinical characteristics including survival. METHODS: In 144 patients with ovarian tumours from a Caucasian population, polymorphisms of MMP-14 (+7096 and...
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