Article
[Association of SNPs in the promoter of MMP-2 and TIMP-2 genes with epithelial ovarian cancer].
Yi chuan = Hereditas - 1 Apr 2008
Li Xiu-Lan, Kang Shan, Zhao Xi-Wa, Zhang Xiao-Juan, Zhou Rong-Miao, Wang Na, Jia Jing-Hui, Zhao Jian, Li Yan
Abstract excerpt
The association between single nucleotide polymorphisms (SNPs) in the promoter region of MMP-2 and TIMP-2 genes and the risk of epithelial ovarian cancer was investigated. MMP-2 C-1306T, C-735T and TIMP-2 G-418C SNPs were genotyped by polymerase chain reaction-restrictive fragment length polymorphism (PCR-RFLP) analysis in 246 patients with epithelial ovarian cancer and 324 healthy women as control. Results...
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