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Matrix metalloproteinase-8 promoter gene polymorphisms in Mexican women with ovarian cancer.

Medical oncology (Northwood, London, England) - 1 Aug 2014

Arechavaleta-Velasco Fabian, Cuevas-Antonio Rocio, Dominguez-Lopez Pablo, Estrada-Moscoso Isaias, Imani-Razavi Fazlollah Shahram, Zeferino-Toquero Moises, Diaz-Cueto Laura

Abstract excerpt

Increased levels of matrix metalloproteinase-8 (MMP-8) have been associated with tumor grade and stage in ovarian cancer. Also, it has been reported that higher concentrations of this enzyme in fluid from malignant ovarian cysts compared with benign ovarian cysts. However, no genetic analysis has been conducted yet to assess the contribution of MMP-8 polymorphisms in ovarian cancer. Thus, this study was performed...

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PMID: 25034366
DOI: 10.1007/s12032-014-0132-3

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