Article
Matrix metalloproteinase-1 gene promoter polymorphism and risk of ovarian cancer.
Journal of the Society for Gynecologic Investigation - 1 Sept 2003
Wenham Robert M, Calingaert Brian, Ali Shazia, McClean Kia, Whitaker Regina, Bentley Rex, Lancaster Johnathan M, Schildkraut Joellen, Marks Jeffrey, Berchuck Andrew
Abstract excerpt
OBJECTIVE: It has been suggested that the 2G allele of a guanine insertion-deletion promoter polymorphism in the promoter of the matrix metalloproteinase-1 (MMP1) gene may increase susceptibility to ovarian cancer. The 2G allele also has been associated with increased MMP1 expression. We investig...
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