Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Matrix metalloproteinase-1 gene promoter polymorphism and risk of ovarian cancer.

Journal of the Society for Gynecologic Investigation - 1 Sept 2003

Wenham Robert M, Calingaert Brian, Ali Shazia, McClean Kia, Whitaker Regina, Bentley Rex, Lancaster Johnathan M, Schildkraut Joellen, Marks Jeffrey, Berchuck Andrew

Abstract excerpt

OBJECTIVE: It has been suggested that the 2G allele of a guanine insertion-deletion promoter polymorphism in the promoter of the matrix metalloproteinase-1 (MMP1) gene may increase susceptibility to ovarian cancer. The 2G allele also has been associated with increased MMP1 expression. We investigated the relationship between the MMP1 polymorphism and ovarian cancer risk in a large population-based, case-control...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Heterozygote
Share to Homozygote

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Matrix Metalloproteinase 1

Share to Neoplasm Invasiveness

Share to Odds Ratio

Share to Oligonucleotide Array Sequence Analysis

Share to Ovarian Neoplasms

Share to Promoter Regions, Genetic

Source

Identifiers

PMID: 12969782
DOI: 10.1016/s1071-5576(03)00141-2

Genes

MMP1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Matrix metalloproteinase-1 gene promoter polymorphism and risk of ovarian cancer.PMID 12969782Read ↗

Matrix metalloproteinase-1 promoter polymorphism 1G/2G is correlated with colorectal cancer invasiveness.Semantic proximity Read ↗

[Association of single nucleotide polymorphism in matrix metalloproteinases promoter with susceptibility to ovarian cancer].Semantic proximity Read ↗

A single nucleotide polymorphism in the matrix metalloproteinase-1 promoter in endometrial carcinomas.Semantic proximity Read ↗

The collagenase-1 (MMP-1) gene promoter polymorphism - 1607/2G is associated with favourable prognosis in patients with colorectal cancer.Semantic proximity Read ↗

Analysis of the Association of Matrix Metalloproteinase-1 Gene Promoter (rs1799750) Polymorphism and Risk of Ovarian Cancer.Semantic proximity Read ↗

Potential for the 2G single nucleotide polymorphism in the promoter of matrix metalloproteinase to enhance gene expression in normal stromal cells.Semantic proximity Read ↗

Association between matrix metalloproteinases polymorphisms and ovarian cancer risk: A meta-analysis and systematic review.Semantic proximity Read ↗

An association between the matrix metalloproteinase 1 promoter gene polymorphism and lymphnode metastasis in breast cancer.Semantic proximity Read ↗

Analysis of matrix metalloproteinase-1 gene polymorphisms and expression in benign and malignant breast tumors.Semantic proximity Read ↗

Matrix metalloproteinase-8 promoter gene polymorphisms in Mexican women with ovarian cancer.Semantic proximity Read ↗

Genetic variants in matrix metalloproteinase genes as disposition factors for ovarian cancer risk, survival, and clinical outcome.Semantic proximity Read ↗

Analysis of two polymorphisms in the promoter region of matrix metalloproteinase 1 and 3 genes in women with endometriosis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.