Article

Synergistic inter-clonal cooperation involving crosstalk, co-option and co-dependency can enhance the invasiveness of genetically distant cancer clones

2023-01-09

Abstract excerpt

<h4>Background: </h4> Despite intensive research, cancer remains a major health problem. The difficulties in treating cancer are due to the complex nature of this disease, including high levels of heterogeneity within tumours. Intra-tumour heterogeneity creates the conditions for inter-clonal competition and selection, which should result in selective sweeps and a reduction in levels of heterogeneity. However, in...

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Literature Corpus work: e6676cce-8b4a-5063-9459-8d89c768fd79
DOI: 10.21203/rs.3.rs-2394919/v1

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