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LobSig is a multigene predictor of outcome in invasive lobular carcinoma

27 Jun 2019

Abstract excerpt

Abstract Invasive lobular carcinoma (ILC) is the most common special type of breast cancer, and is characterized by functional loss of E-cadherin, resulting in cellular adhesion defects. ILC typically present as estrogen receptor positive, grade 2 breast cancers, with a good short-term prognosis. Several large-scale molecular profiling studies have now dissected the unique genomics of ILC. We have undertaken an...

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PMID: 31263747
DOI: 10.1038/s41523-019-0113-y

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