Article
Lobular and ductal carcinomas of the breast have distinct genomic and expression profiles.
Oncogene - 11 Sept 2008
Bertucci F, Orsetti B, Nègre V, Finetti P, Rougé C, Ahomadegbe J-C, Bibeau F, Mathieu M-C, Treilleux I, Jacquemier J, Ursule L, Martinec A, Wang Q, Bénard J, Puisieux A, Birnbaum D, Theillet C
Abstract excerpt
Invasive ductal carcinomas (IDCs) and invasive lobular carcinomas (ILCs) are the two major pathological types of breast cancer. Epidemiological and histoclinical data suggest biological differences, but little is known about the molecular alterations involved in ILCs. We undertook a comparative large-scale study by both array-compared genomic hybridization and cDNA microarray of a set of 50 breast tumors (21...
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