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Article

Genome-wide meta-analysis of muscle weakness identifies 15 susceptibility loci in older men and women

2020-05-21

Abstract excerpt

Low muscle strength is an important heritable indicator of poor health linked to morbidity and mortality in older people. In a genome-wide association study meta-analysis of 256,523 Europeans aged 60 years and over from 22 cohorts we identified 15 loci associated with muscle weakness (European Working Group on Sarcopenia in Older People definition: n=48,596 cases, 18.9% of total), including 12 loci not implicated...

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Literature Corpus work
9466c180-eb83-5dda-bd6d-ffa7b9dd2c03
DOI
10.1101/2020.05.14.20100354
Open publication

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Genome-wide meta-analysis of muscle weakness identifies 15 susceptibility loci in older men and womenDOI 10.1101/2020.05.14.20100354
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