Article
From bench to bedside: Clinical implications of KRAS status in patients with colorectal liver metastasis.
Surgical oncology - 1 Sept 2016
Andreatos Nikolaos, Ronnekleiv-Kelly Sean, Margonis Georgios A, Sasaki Kazunari, Gani Faiz, Amini Neda, Wilson Ana, Pawlik Timothy M
Abstract excerpt
INTRODUCTION: While the role of KRAS in the molecular genetics of colorectal cancer has been studied extensively, its prognostic impact in colorectal liver metastases (CRLM) has only recently been examined. This review aimed to summarize currently reported findings on the clinical implications of KRAS mutant (mut-KRAS) status for patients with CRLM. MATERIALS AND METHODS: The Pubmed database was searched for...
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