Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Incidence and prognostic impact of KRAS and BRAF mutation in patients undergoing liver surgery for colorectal metastases.

Cancer - 1 Dec 2013

Karagkounis Georgios, Torbenson Michael S, Daniel Hubert D, Azad Nilofer S, Diaz Luis A, Donehower Ross C, Hirose Kenzo, Ahuja Nita, Pawlik Timothy M, Choti Michael A

Abstract excerpt

BACKGROUND: Molecular biomarkers offer the potential for refining prognostic determinants in patients undergoing cancer surgery. Among patients with colorectal cancer, KRAS and BRAF are important biomarkers, but their role in patients undergoing surgical therapy for liver metastases is unknown. In this study, the incidence and prognostic significance of KRAS and BRAF mutations were determined in patients...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Disease-Free Survival
Share to Hepatectomy

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Liver Neoplasms

Share to Neoadjuvant Therapy

Share to Proto-Oncogene Proteins

Share to Proto-Oncogene Proteins B-raf

Share to Proto-Oncogene Proteins p21(ras)

Share to ras Proteins

Source

Open in PubMed Open full text

Identifiers

PMID: 24104864
DOI: 10.1002/cncr.28347
PMCID: PMC3967132

Genes

KRAS
BRAF

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Incidence and prognostic impact of KRAS and BRAF mutation in patients undergoing liver surgery for colorectal metastases.PMID 24104864Read ↗

Clinical significance and prognostic relevance of KRAS, BRAF, PI3K and TP53 genetic mutation analysis for resectable and unresectable colorectal liver metastases: A systematic review of the current evidence.Semantic proximity Read ↗

From bench to bedside: Clinical implications of KRAS status in patients with colorectal liver metastasis.Semantic proximity Read ↗

Mutation Status of RAS, TP53 , and SMAD4 is Superior to Mutation Status of RAS Alone for Predicting Prognosis after Resection of Colorectal Liver MetastasesSemantic proximity Read ↗

KRAS mutation influences recurrence patterns in patients undergoing hepatic resection of colorectal metastases.Semantic proximity Read ↗

Impact of BRAF mutations on clinical outcomes following liver surgery for colorectal liver metastases: An updated meta-analysis.Semantic proximity Read ↗

Association of BRAF Mutations With Survival and Recurrence in Surgically Treated Patients With Metastatic Colorectal Liver Cancer.Semantic proximity Read ↗

BRAF mutations and survival with surgery for colorectal liver metastases: A systematic review and meta-analysis.Semantic proximity Read ↗

The impact of KRAS mutations on prognosis in surgically resected colorectal cancer patients with liver and lung metastases: a retrospective analysis.Semantic proximity Read ↗

BRAF mutation is a prognostic biomarker for colorectal liver metastasectomy.Semantic proximity Read ↗

Effect of KRAS and BRAF Mutations on Survival of Metastatic Colorectal Cancer After Liver Resection: A Systematic Review and Meta-Analysis.Semantic proximity Read ↗

Effect of KRAS Mutation on Long-Term Outcomes of Patients Undergoing Hepatic Resection for Colorectal Liver Metastases.Semantic proximity Read ↗

Prognostic Role of BRAF Mutations in Colorectal Cancer Liver Metastases.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.