Association Between CHEK2*1100delC and Breast Cancer: A Systematic Review and Meta-Analysis.

doi:10.1007/s40291-018-0344-x

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Article

Association Between CHEK2*1100delC and Breast Cancer: A Systematic Review and Meta-Analysis.

Molecular diagnosis & therapy - 1 Aug 2018

Liang Mingming, Zhang Yun, Sun Chenyu, Rizeq Feras Kamel, Min Min, Shi Tingting, Sun Yehuan

Abstract excerpt

INTRODUCTION: The association between the checkpoint kinase 2*1100delC (CHEK2*1100delC) and breast cancer has been extensively explored. OBJECTIVE: In light of the recent publication of studies on these specific findings, particularly regarding male patients with breast cancer, we performed an updated meta-analysis to investigate a more reliable estimate. METHODS: This meta-analysis included 26 published studies...

Topics

Alleles
Biomarkers, Tumor
Breast Neoplasms
Case-Control Studies
Checkpoint Kinase 2
Female
Genetic Association Studies
Genetic Predisposition to Disease
Genotype
Heterozygote
Humans

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Male

Odds Ratio

Publication Bias

Risk Assessment

Risk Factors

Sequence Deletion

Source

Open in PubMed

Identifiers

PMID: 29909568
DOI: 10.1007/s40291-018-0344-x

Genes

CHEK2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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