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T‐cell receptor sequencing demonstrates persistence of virus‐specific T cells after antiviral immunotherapy

20 Jun 2019

Abstract excerpt

Viral infections are a serious cause of morbidity and mortality following haematopoietic stem cell transplantation (HSCT). Adoptive cellular therapy with virus-specific T cells (VSTs) has been successful in preventing or treating targeted viruses in prior studies, but the composition of ex vivo expanded VST and the critical cell populations that mediate antiviral activity in vivo are not well defined. We utilized...

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PMID: 31219185
DOI: 10.1111/bjh.16053

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