Article
Quantitative assessment of T cell repertoire recovery after hematopoietic stem cell transplantation.
Nature medicine - 1 Mar 2013
van Heijst Jeroen W J, Ceberio Izaskun, Lipuma Lauren B, Samilo Dane W, Wasilewski Gloria D, Gonzales Anne Marie R, Nieves Jimmy L, van den Brink Marcel R M, Perales Miguel A, Pamer Eric G
Abstract excerpt
Delayed T cell recovery and restricted T cell receptor (TCR) diversity after allogeneic hematopoietic stem cell transplantation (allo-HSCT) are associated with increased risks of infection and cancer relapse. Technical challenges have limited faithful measurement of TCR diversity after allo-HSCT....
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