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STAT3 Activation and Oncogenesis in Lymphoma

19 Dec 2019

Abstract excerpt

Signal transducer and activator of transcription 3 (STAT3) is an important and the most studied transcription factor in the Janus kinase (JAK)/STAT signaling pathway. STAT3 mediates the expression of various genes that play a critical role in many cellular and biological processes, such as cell proliferation, survival, differentiation, migration, angiogenesis, and inflammation. STAT3 and associated JAKs are...

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PMID: 31861597
DOI: 10.3390/cancers12010019

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