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Article

Distribution of DNA damage in the human sperm nucleus: implications of the architecture of the sperm head

4 Jun 2019

Abstract excerpt

The sperm nucleus is prone to sustain DNA damage before and after ejaculation. Distribution of the damage is not homogeneous, and the factors determining differential sensitivity among nuclear regions have not yet been characterized. Human sperm chromatin contains three structural domains, two of which are considered the most susceptible to DNA damage: the histone bound domain, harboring developmental related...

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Identifiers

PMID: 31210149
DOI: 10.4103/aja.aja_26_19

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