Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The Impact of Single- and Double-Strand DNA Breaks in Human Spermatozoa on Assisted Reproduction

29 May 2020

Abstract excerpt

Several cellular insults can result in sperm DNA fragmentation either on one or both DNA strands. Oxidative damage, premature interruption of the apoptotic process and defects in DNA compaction during spermatogenesis are the main mechanisms that cause DNA breaks in sperm. The two-tailed Comet assay is the only technique that can differentiate single- (SSBs) from double- (DSBs) strand DNA breaks. Increased levels...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Reproductive Biology and Fertility
Share to Reproductive Health and Technologies
Share to Sperm and Testicular Function

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 32485940
DOI: 10.3390/ijms21113882

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The Impact of Single- and Double-Strand DNA Breaks in Human Spermatozoa on Assisted ReproductionPMID 32485940Read ↗

Single and Double Strand Sperm DNA Damage: Different Reproductive Effects on Male FertilitySemantic proximity Read ↗

A systematic review and meta-analysis to determine the effect of sperm DNA damage on in vitro fertilization and intracytoplasmic sperm injection outcomeSemantic proximity Read ↗

Sperm DNA damage and its impact on male reproductive health: a critical review for clinicians, reproductive professionals and researchersSemantic proximity Read ↗

Using the alkaline comet assay in prognostic tests for male infertility and assisted reproductive technology outcomesSemantic proximity Read ↗

Clinical implications of sperm DNA damageSemantic proximity Read ↗

DNA damage in testicular germ cells and spermatozoa. When and how is it induced? How should we measure it? What does it mean?Semantic proximity Read ↗

DNA double strand breaks in human spermatozoa can be predictive for assisted reproductive outcomeSemantic proximity Read ↗

Sperm DNA Fragmentation: causes, evaluation and management in male infertilitySemantic proximity Read ↗

Innovative technology for evaluation of sperm DNA double-strand breaks diagnoses male factor infertility and prevents reproductive failuresSemantic proximity Read ↗

Sperm DNA damage diagnostics: when and whySemantic proximity Read ↗

Sperm DNA Fragmentation in Reproductive MedicineSemantic proximity Read ↗

Progress in Research on Sperm DNA FragmentationSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.