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Article

SPTBN1 and cancer, which links?

17 Jun 2019

Abstract excerpt

SPTBN1 is a dynamic intracellular nonpleckstrin homology-domain protein, functioning as a transforming growth factor-β signal transducing adapter protein which is necessary to form Smad3/Smad4 complex. Recently SPTBN1 is considered to be associated with many kinds of cancers. SPTBN1 expression and function differ between different tumor states or types. This review summarizes the recent advances in the expression...

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PMID: 31206681
DOI: 10.1002/jcp.28975

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