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SPTBN2 regulated by miR-214-3p inhibits the proliferation and migration of colorectal cancer cells

20 Dec 2023

Abstract excerpt

Colorectal cancer (CRC) is one of the most common and lethal malignancies. According to our analysis in the GEPIA database, SPTBN2 was found to be significantly elevated in COAD patients.Western blot also verified this result, and SPTBN2 was highly expressed in two types of colorectal cancer cells, Caco2 and HCT-8. Therefore, we knocked down SPTBN2 to investigate its function in colorectal cancer, and the results...

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PMID: 38279463
DOI: 10.14715/cmb/2023.69.14.20

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