Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Multi-omics pan-cancer study of SPTBN2 and its value as a potential therapeutic target in pancreatic cancer.

Scientific reports - 29 Apr 2024

Chang Hongliang, Chen Hong, Ma Taiheng, Ma Kexin, Li Yi, Suo Lida, Liang Xiangnan, Jia Kunyu, Ma Jiahong, Li Jing, Sun Deguang

Abstract excerpt

SPTBN2 is a protein-coding gene that is closely related to the development of malignant tumors. However, its prognostic value and biological function in pan-cancer, especially pancreatic cancer (PAAD), have not been reported. In the present study, a novel exploration of the value and potential mechanism of SPTBN2 in PAAD was conducted using multi-omics in the background of pan-cancer. Via various database...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Biomarkers, Tumor
Share to DNA Methylation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Expression Regulation, Neoplastic

Share to Multiomics

Share to Mutation

Share to Pancreatic Neoplasms

Share to Prognosis

Share to Spectrin

Source

Open in PubMed Open full text

Identifiers

PMID: 38684762
DOI: 10.1038/s41598-024-60780-6
PMCID: PMC11059406

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Multi-omics pan-cancer study of SPTBN2 and its value as a potential therapeutic target in pancreatic cancer.PMID 38684762Read ↗

Integration of Single-Cell RNA Sequencing and Bulk RNA Sequencing Reveals That TAM2-Driven Genes Affect Immunotherapeutic Response and Prognosis in Pancreatic CancerSemantic proximity Read ↗

Survival Analysis of Multi-Omics Data Identifies Potential Prognostic Markers of Pancreatic Ductal AdenocarcinomaSemantic proximity Read ↗

Comprehensive machine-learning survival framework develop a consensus model in large scale multi-center cohorts for pancreatic cancerSemantic proximity Read ↗

Machine learning identifies SLC6A14 as a novel biomarker promoting the proliferation and metastasis of pancreatic cancer via Wnt/β-catenin signalingSemantic proximity Read ↗

Molecular classification and prognosis study of pancreatic ductal adenocarcinoma through multi-omics integrated clustering analysis.Semantic proximity Read ↗

Application of multiomics sequencing and advances in the molecular mechanisms of pancreatic neuroendocrine neoplasms.Semantic proximity Read ↗

Comprehensive Genomic Analysis of the Prognostic and Immunological Characteristics of Tertiary Lymphoid structures and CD8+ T-cells in Pancreatic Ductal AdenocarcinomaSemantic proximity Read ↗

An integrative pan-cancer analysis of COPB1 based on data miningSemantic proximity Read ↗

Pan-cancer analysis of ARMCX genes identifies ARMCX1 as a novel suppressor gene for pancreatic carcinomaSemantic proximity Read ↗

UBE2C : A pan‐cancer diagnostic and prognostic biomarker revealed through bioinformatics analysisSemantic proximity Read ↗

Pan-cancer analysis of PTPN6: prognostic significance and functional implications in tumor progressionSemantic proximity Read ↗

Comprehensive multi-omics profiling identifies novel molecular subtypes of pancreatic ductal adenocarcinomaSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.