Article

Down-regulation of TAK1 inhibits migration and invasion of p-NENs by regulating JNK signaling pathway through interaction with PDZD2

2024-05-07

Abstract excerpt

<title>Abstract</title> <p>Pancreatic neuroendocrine neoplasmas (p-NENs) is a rare type of disease among digestive malignancy tumors, but its mechanics are still unclear. It has been found that TAK1 plays a crucial role in the progression of many tumors. We discovered TAK1 was highly expressed in BON-1 compared to two other pancreatic cell lines（CFPAC-1and hTERT-HPNE). Inhibition of TAK1 could significantly suppr...

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Literature Corpus work: 5a841c6a-e219-5c57-8b82-6c261baad916
DOI: 10.21203/rs.3.rs-4325473/v1

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