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Article

Evidence for genetic correlation between human cerebral white matter microstructure and inflammation.

Human brain mapping - 1 Oct 2019

Rodrigue Amanda L, Knowles Emma Em, Mollon Josephine, Mathias Samuel R, Koenis Marinka Mg, Peralta Juan M, Leandro Ana C, Fox Peter T, Sprooten Emma, Kochunov Peter, Olvera Rene L, Duggirala Ravindranath, Almasy Laura, Curran Joanne E, Blangero John, Glahn David C

Abstract excerpt

White matter microstructure is affected by immune system activity via the actions of circulating pro-inflammatory cytokines. Although white matter microstructure and inflammatory measures are significantly heritable, it is unclear if overlapping genetic factors influence these traits in humans. We conducted genetic correlation analyses of these traits using randomly ascertained extended pedigrees from the...

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Identifiers

PMID: 31187567
DOI: 10.1002/hbm.24694
PMCID: PMC6707845

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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