Article
New discoveries in the genetics and genomics of systemic juvenile idiopathic arthritis.
Expert review of clinical immunology - 1 Sept 2024
Correia Marques Mariana, Ombrello Michael J, Schulert Grant S
Abstract excerpt
INTRODUCTION: Systemic juvenile idiopathic arthritis (sJIA) is a severe inflammatory condition with onset in childhood. It is sporadic, but elements of its stereotypical innate immune responses are likely genetically encoded by both common variants with small effect sizes and rare variants with larger effects. AREAS COVERED: Genomic investigations have defined the unique genetic architecture of sJIA....
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