Article
Siva plays a critical role in mouse embryonic development.
Cell death and differentiation - 1 Jan 2020
Jacobs Suzanne B R, Van Nostrand Jeanine L, Bowen Margot E, Baker Julie C, Attardi Laura D
Abstract excerpt
The Siva protein, named after the Hindu God of Destruction, plays important roles in apoptosis in various contexts, including downstream of death receptor activation or p53 tumor suppressor engagement. The function of Siva in organismal development and homeostasis, however, has remained uncharacterized. Here, we generate Siva knockout mice to characterize the physiological function of Siva in vivo. Interestingly,...
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