Death before birth: clues from gene knockouts and mutations.

Abstract excerpt

A survey of mouse gene knockouts, transgene insertions and spontaneous mutations that are lethal prenatally reveals that surprisingly few developmental disturbances lead to death of the embryo and early foetus. These disturbances include failure to establish and maintain a vascular circulation, and failure to make the transition from yolk-sac-based to liver-based haematopoiesis. The embryo must also establish...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Morphogenesis
• Share to Mutation
• Share to Embryonic and Fetal Development