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Temporal and spatial expression of tight junction genes during zebrafish pronephros development

1 Nov 2014

Abstract excerpt

The kidney is comprised of nephrons - epithelial tubes with specialized segments that reabsorb and secrete solutes, perform osmoregulation, and produce urine. Different nephron segments exhibit unique combinations of ion channels, transporter proteins, and cell junction proteins that govern permeability between neighboring cells. The zebrafish pronephros is a valuable model to study the mechanisms of vertebrate...

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PMID: 25460834
DOI: 10.1016/j.gep.2014.11.001

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