Article
Genetic Correlations Between Diabetes and Glaucoma: An Analysis of Continuous and Dichotomous Phenotypes.
American journal of ophthalmology - 1 Oct 2019
Laville Vincent, Kang Jae H, Cousins Clara C, Iglesias Adriana I, Nagy Réka, Cooke Bailey Jessica N, Igo Robert P, Song Yeunjoo E, Chasman Daniel I, Christen William G, Kraft Peter, Rosner Bernard A, Hu Frank, Wilson James F, Gharahkhani Puya, Hewitt Alex W, Mackey David A, Hysi Pirro G, Hammond Christopher J, vanDuijn Cornelia M, Haines Jonathan L, Vitart Veronique, Fingert John H, Hauser Michael A, Aschard Hugues, Wiggs Janey L, Khawaja Anthony P, MacGregor Stuart, Pasquale Louis R
Abstract excerpt
PURPOSE: A genetic correlation is the proportion of phenotypic variance between traits that is shared on a genetic basis. Here we explore genetic correlations between diabetes- and glaucoma-related traits. DESIGN: Cross-sectional study. METHODS: We assembled genome-wide association study summary statistics from European-derived participants regarding diabetes-related traits like fasting blood sugar (FBS) and type...
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