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Article

Sensitive bioluminescence imaging of fungal dissemination to the brain in mouse models of cryptococcosis

17 May 2019

Abstract excerpt

ABSTRACT Cryptococcus neoformans is a leading cause of fungal brain infection, but the mechanism of dissemination and dynamics of cerebral infection following pulmonary disease are poorly understood. To address these questions, non-invasive techniques that can study the dynamic processes of disease development and progression in living animal models or patients are required. As such, bioluminescence imaging (BLI)...

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PMID: 31101657
DOI: 10.1242/dmm.039123

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