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Article

Genetic association and drug target exploration of inflammation-related proteins with risk of major depressive disorder.

Progress in neuro-psychopharmacology & biological psychiatry - 10 Jan 2025

Sun Wenxi, Cao Hongbao, Liu Dongming, Baranova Ancha, Zhang Fuquan, Zhang Xiaobin

Abstract excerpt

BACKGROUND: In numerous observational studies, circulating inflammation-related proteins have been linked with major depressive disorder (MDD), yet the precise causal direction of this relationship remains unclear. This study aims to investigate the potential causal link between inflammation-related proteins and the risk of developing MDD. METHODS: We utilized summary data from a genome-wide association study...

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Source

Identifiers

PMID: 39383931
DOI: 10.1016/j.pnpbp.2024.111165

Genes

CD40
HGF
SLAMF1
TGFA
CCL19
IL20RA
TNFSF14

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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