Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Investigating the epigenetic profile of the inflammatory gene IL-6 in late-life depression.

BMC psychiatry - 25 Oct 2017

Ryan Joanne, Pilkington Lauren, Neuhaus Katharina, Ritchie Karen, Ancelin Marie-Laure, Saffery Richard

Abstract excerpt

BACKGROUND: It is well established that there is a link between inflammation and depression, with several studies reporting increased circulating levels of the pro-inflammatory cytokine, interleukin-6 (IL6), in depressed individuals. Peripheral epigenetic marks, including DNA methylation, hold promise as biomarkers for a range of complex conditions, with potential to inform diagnosis and tailor interventions. The...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aged
Share to Depressive Disorder, Major

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Diagnostic and Statistical Manual of Mental Disorders

Share to DNA Methylation

Share to Follow-Up Studies

Share to France

Share to Genetic Variation

Share to Interleukin-6

Source

Open in PubMed Open full text

Identifiers

PMID: 29070016
DOI: 10.1186/s12888-017-1515-8
PMCID: PMC5657056

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Investigating the epigenetic profile of the inflammatory gene IL-6 in late-life depression.PMID 29070016Read ↗

DNA methylation and inflammation marker profiles associated with a history of depression.Semantic proximity Read ↗

Association study of polymorphisms within inflammatory genes and methylation status in treatment response in major depressionSemantic proximity Read ↗

Physical health and incident late-life depression: modification by cytokine genes.Semantic proximity Read ↗

Genetic Contributions of Inflammation to DepressionSemantic proximity Read ↗

A methylome-wide association study of major depression with out-of-sample case-control classification and trans-ancestry comparisonSemantic proximity Read ↗

‘Inflammaging’ in Major Depressive Disorder: Associations between markers of inflammation and brain ageing in depression across two large community-based cohortsSemantic proximity Read ↗

Assessing 42 inflammatory markers in 321 control subjects and 887 major depressive disorder cases: BMI and other confounders and overall predictive ability for current depressionSemantic proximity Read ↗

The inflammatory cytokines: molecular biomarkers for major depressive disorder?Semantic proximity Read ↗

Dynamic Epigenetic Changes During Antidepressant Pharmacotherapy in Major Depressive DisorderSemantic proximity Read ↗

DNA methylation signatures of C-reactive protein associations with structural neuroimaging measures and major depressive disorderSemantic proximity Read ↗

Identification of IL6 as a susceptibility gene for major depressive disorder.Semantic proximity Read ↗

Complex Neurobiological Mechanisms and Risk Factors Underlying Late-Life Depression.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.